Billing methods, billable items, and other fees for Genomics Analysis Platform-genomics-阿里云帮助中心

This topic describes the billing methods, billable items, and associated fees for other Alibaba Cloud products that are used with Genomics Analysis Platform.

Overview

Genomics Analysis Platform is a fully managed, serverless genomics computing service from Alibaba Cloud. It is elastic and provisions resources on demand, so you do not need to create or manage clusters. The platform supports any sample size, from a single sample to tens of millions of samples. You pay only for what you use, which makes it a flexible, economical, and easy-to-manage service.

Billing method

A genomics data analytics workflow usually consists of one or more steps. Alibaba Cloud Genomics Analysis Platform uses Workflow Description Language (WDL), supported by the Global Alliance for Genomics and Health (GA4GH), to define bioinformatics analysis applications. WDL describes the required compute resources, execution environment, and dependencies for each step in a standardized and parameterized way.

Tasks submitted using these analysis applications are parsed by the workflow execution engine into multiple backend compute jobs. The platform automatically and intelligently processes these jobs in parallel until the task is complete.

Genomics Analysis Platform uses a pay-as-you-go billing method. You are charged for the platform resources that are consumed. The basic billing unit is a compute job within a task. Billing is calculated in one-minute increments from the time a compute job starts until it is released. Usage for less than one minute is billed as one minute. Fees are deducted in real time, and bills are generated hourly. (Bills are typically generated one hour after the current billing cycle ends. The actual billing time is subject to the system.)

Billable items and pricing

You can specify the platform resources for a single compute job using the runtime properties of the step in the analysis application. The supported resource types, specifications, and their corresponding WDL definitions are described in the following table:

Resource type	Description	Specification	WDL definition	Notes
Compute instance	The execution environment for compute jobs, such as containers, x86, GPU, or FPGA.	vCPU	cpu:1	vCPU and memory are used together and must meet the Limits.
		Memory	memory:"2G"	vCPU and memory are used together and must meet the Limits.
		ECS instance	instanceType:"ecs.c5.xlarge"	Using an ECS instance overwrites the vCPU and memory settings.
Compute storage	Localized storage for the input and output files of a compute job.	Capacity NAS	disks:"local-disk 20G nas_cap"	Can be used as a data disk. For more information, see Set runtime properties.
		Performance NAS	disks:"local-disk 100G nas_per"
		Enterprise SSD (ESSD)	disks:"local-disk 100G cloud_essd"
Software/Algorithm	Software tools used by the compute job.	Third-party software	docker: "registry-vpc.cn-shenzhen.aliyuncs.com/easy-gene/genomes-in-the-cloud:1.0"	Only Alibaba Cloud Container Registry and the platform's built-in third-party software list are supported.

The billable items and pricing for platform resources are as follows:

Billable item	Description	Price	Public preview promotion*
instance_type	Compute instance type	ECS Pricing	During the public preview, data pull, data pushback, and image pull times are free of charge for a limited time.
gpu_type	GPU type	gc4.medium: CNY 13/hour gc5.medium: CNY 15/hour gc7.small: CNY 14/hour
cpu	Number of cores	CNY 0.17640/core/hour
mem	Memory	CNY 0.02207/GiB/hour
nas_cap	Capacity NAS	CNY 0.00049/GiB/hour
nas_per	Performance NAS	CNY 0.0025694/GiB/hour
cloud_essd	ESSD PL0	CNY 0.001155/GiB/hour
cloud_essd_pl1	ESSD PL1	CNY 0.00231/GiB/hour
software	Software/Algorithm	Third-party software pricing

Note

Compute resources are billed by the minute. Usage for less than one minute is billed as one minute. During the public preview, storage resources are also billed by the minute. Usage for less than one minute is billed as one minute.

Billing example

This example shows the billing for analyzing a 30x whole-genome sequencing (WGS) sample using the damo/dna-variant-calling application in Genomics Analysis Platform.

The billing details are as follows:

30x WGS sample, ~90 GBase fastq file
Total cost for a 1.53-hour analysis using the damo/dna-variant-calling:v1.0.11 application
Application step	Number of parallel jobs	Runtime	Billable item	Specification	Unit price (CNY)	Subtotal (CNY)	Cost per step (compute job)	Total cost per sample (task)
FastqToVcf	1	1.53 h	instance_type	gc5.medium	15.00	22.95	23.93	23.93
			nas_per	250 GB	0.0025694	0.98
			software	damo	0.00	0.00

The billing logic for a single compute job is as follows:

Fee = (Unit price of specification + Unit price of Performance NAS × NAS capacity + Unit price of software) × Runtime

The total cost for a task in Genomics Analysis Platform is the sum of the costs of all compute jobs that correspond to the steps in the analysis application.

Billing for other Alibaba Cloud products

Running analysis tasks in Genomics Analysis Platform requires other Alibaba Cloud products, which may incur additional fees as described in the following table:

Dependencies on cloud products	Purpose	Fee type	Billing details	Notes
Object Storage Service (OSS) Standard	Store genomics data	Storage fee	Pay-as-you-go at CNY 0.12/GB/month. Resource plans are also available.	For more information, see the OSS product documentation.
Object Storage Service (OSS) Standard	Download data files	Traffic fee	00:00–08:00 (off-peak): CNY 0.25/GB 08:00–24:00 (peak): CNY 0.50/GB	For more information, see the OSS product documentation.
Container Registry (ACR) Personal Edition	The custom tool images used in WDL. This setting is for Docker only.	/	Personal Edition is free of charge.	For more information, see the ACR product documentation.